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Abstract Objective To evaluate the impact of optimal transfer process on reperfusion time and prognosis of pa-tients with ST-segment elevation myocardial infarction (STEMI). Methods 122 patients with STEMI were referred from county hospitals for primary PCI from January 2009 to December 2010. Of them, 58 cases (control group) were transferred to emergency department (ED) and then to catheter lab after evaluated by cardiologists. 64 cases (optimal group) were referred directly to catheter lab bypass ED. Door1-bal oon (D1-B) time, door1-door2 (D1-D2) time and door2-bal oon (D2-B) time were recorded. Creatine kinase-MB and troponin I were measured. The mortality and major adverse cardiac events during hospitalization and 30 days fol ow-up were analyzed. Results D1-B time and D2-B time were signifi-cantly shorter,peak creatine kinase-MB and troponin I were lower in optimal group than in control group (103.9±16.1 vs 164.8±14.7min, 23.0±6.4 vs 87.4±12.7min, 252.6±201.7vs 387.2±291.4 U/L, 42.1±30.7 vs 57.8±31.2ng/ml, al P<0.01). Major adverse cardiac events were lower, although mortality was similar, in optimal group than in control group (9.4% vs 25.9%, P<0.05;12.5% vs 32.8%, P<0.01). Conclusion Door to bol oon time may be shorted when patients are referred directly to catheter lab for primary PCI bypass ED, which may improve clinical prognosis.
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