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Abstract Objective To determine the association of admission hyperglycemia with short- term outcome of patients with acute heart failure (AHF). Methods Blood samples were col ected at the second day morning after admission for measuring blood glucose, insulin, hepatic and renal function, NT- pro brain natriuretic peptide (NT- Pro BNP) in 150 AHF patients. Multivariate Logistic regression analysis and receiver operating characteristic (ROC) curve were performed for analyzing relative factors with the severity of AHF and al- cause mortality within 30 days. Results (1)Patients were divided into Q1~Q4 group by quartile of admission blood glucose. Length of stay was significantly longer in Q3 and Q4 groups than Q1 and Q2 groups(P<0.05). 30- day al- cause mortality increased from Q1to Q4 with significant difference between groups (P<0.05). (2) The admission hyperglycemia was an independent predictor of 30- day mortality in AHF. The risk of mortality increased by 1.26- fold for every 1 mmol/L increase in blood glucose [OR (95%CI) 1.352 (1.061~1.511), P<0.01]. (3) The sensitivity and specificity for predicting al- cause 30- day mortality were 80%and 51%, respectively, when serum glucose was 8 mmol/L, 52%and 81%when serum glucose was 10 mmol/L. Conclusion Admission hyperglycemia is a marker of the severity of il ness and related to the worse short- term prognosis.
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