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Abstract Objective To explore the value of ECG combined with clinical risk factors in predicting sudden cardiac death (SCD) in patients with acute myocardial infarction (AMI). Methods Collected the patients with AMI suffered malignant ventricular arrhythmia (MVA) in our hospital during January 2011~June 2012 period as malignant arrhythmia group(n=148),the AMI patients not associated with ventricular arrhythmia were selected as control group(n=52). The ECG parameters including QRS width, QT and Tp- e interval、J wave、Fragmented QRS(fQRS) were measured, calculated QTd、Tp- eC and evaluated left ventricular ejection fraction (LVEF) by echocardiography. Al patients were followed up 6 months to investigate the occurrence of MVA and SCD. Compared with the ECG parameters between the two groups. The 200 patients were divided into LVEF≤30%, 30%50% according to LVEF.The relationship among LVEF、VT/VF and SCD was analyzed.Incorporated the common clinical risk factors, the predictors of VT / VF were evaluated by Logistic regression analysis. Results The patients with diabetes in malignant arrhythmia group were more than in control group.The QRS width、QTd、Tp- e interval、Tp- eC、J wave、fQRS、BNP and SCD evidence in malignant arrhythmia group were higher than in the control group (P<0.05 or 0.01), while the LVEF in malignant arrhythmia group was lower than in the control group (P<0.01). With the decrease of LVEF, incidence of VT / VF were gradual y increased, 30%
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