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Abstract Objective To explore the association of non- invasive central blood pressure(CBP) with extent of coronary artery disease (CAD) and plaque characteristics. Methods A total of 207 inpatients with CAD underwent coronary angiography from January2015 to July 2016 were enrol ed and divided into single- vessel disease group (74cases), two- vessel disease group(70 cases) and triple- vessel disease group(63cases) based on angiography results. Of them, 54 cases underwent intravascular ultrasound (IVUS) of target vessels fol owing angiography to evaluate plaque characteristics and calculate vascular remodeling index (RI). CBP was measured by non- invasive method. The association of non- invasive CBP with the number of lesion- vessel and plaque characteristics was analyzed. Results The systolic CBP, pulse pressure (PP), and fractional systolic pressure (FSP) increased and fractional diastolic pressure (FDP) decreased as the number of lesion- vessel increased. Logistic analysis showed that increased PP, FSP and decreased FDP were the risk factors of triple- vessel lesions. PP was positively correlated with RI (r=0.358, P<0.05). Conclusion The non- invasive systolic CBP、PP、FSP and FDP are related with the extent of coronary artery disease. PP is related with coronary vascular remodeling.
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