Abstract Objective To evaluate the influence of age on safety and efficacy of percutaneous coronary intervention (PCI) of acute myocardial infarction (AMI). Methods 348 patients with AMI were retrospectively analyzed and divided into young and middle- aged group (YM group), younger elderly group and elderly group. The clinical characteristics, coronary lesions,PCI outcome were compared among the three groups. Results No ST- segment elevation myocardial infarction and the use of intra- aortic bal oon pump were significantly more in elderly group than in YM group (P<0.05). Single- vessel lesions, especial y anterior descending branch, and thrombosis were seen more in YM group, while moderately severe calcified lesions appeared more in elderly group. These were significantly different between the two groups (P<0.05). Multiple- vessel lesions trended to increase from YM group to elderly group. In elderly group, the complications and mortality of PCI were significantly higher compared with other groups, success rate was significantly lower compared with YM group (al P<0.05). Conclusion The success rate decreases and complications of PCI increase in elderly patients with AMI.
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