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Abstract Objective To explore the feasibility of radiofrequency catheter ablation (RFCA) of right ventricular outflow tract (RVOT) premature ventricular contract (PVC) with a single catheter guided by EnSite Velocity system. Methods 28 patients with symptomatic RVOT PVCs refractory to medicines underwent single- catheter ablation. RVOT electroanatomical map was reconstructed by catheter mapping guided by EnSite Velocity system. PVC loci were localized by activation sequence mapping and pacing mapping. Results The times for electroanatomical reconstruction of RVOT and X- ray exposure were 6.6±2.2 min and 0.5±0.4 min, respectively. RFCA was successful in al cases. PVC originated from septum (17 cases), anterior wal (3 cases), posterior wal (3 cases) and free wal (5 cases).The site of ablation preceded the onset of surface QRS by 34.2±5.1ms. The total procedure time, total X- ray exposure time, mapping time and ablation time were 56.2±13.9 min, 1.1±0.7min, 15.5±8.2 min and 5.5±2.9 min, respectively. Fluoroscopy was not taken in 6 patients. PVC recurred in one patient during fol ow- up of 19.7±8.6 days. No complication occurred. Conclusion RVOT PVCs originate mostly from septum. Single- catheter ablation under the guidance of EnSite Velocity system is safety and effective.
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