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Abstract Objective To investigate the correlation between coronary stenosis severity and left ventricular ejection fraction (LVEF) in patients without myocardial infarction. Methods Coronary angiography and echocardiography performed during the same period were analyzed retrospectively in 261 cases. They were divided into group A (coronary stenosis<50%, n=46) and coronary artery disease (CAD) group (coronary stenosis≥50%, n=215) based on coronary angiography. According to Gensini score (GSS), CAD group was further divided into group B (GSS≤10, n=78) , group C (1040, n=42). The correlation between coronary stenosis severity and LVEF was analyzed. Results (1)The LVEF was significantly lower in group B, C and D than in group A(t=2.52、2.87、4.11, P<0.05), and lower in group D than in group B and C(t=2.36、2.63, P<0.05). (2)There was a mild but significant negative correlation between LVEF and GGS in CAD group (r=-0.21, P<0.05) and in group D (r=-0.36, P<0.05). (3)Patients with two- or three-vessel stenosis≥90%accounted for 9%in those with LVEF>60%and 18%in those with LVEF≤60%(X2=3.91, P<0.05). Conclusion LVEF may decrease more or less in patients with moderate to severe coronary stenosis but no myocardial infarction. There is mild negative correlation between coronary artery disease severity and LVEF.
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