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Abstract Objective To evaluate application value of CT angiography (CTA) in the diagnosis of lower extremity atherosclerosis obliterans (ASO). Methods 91 patients with lower extremity ASO underwent both CTA and digital subtraction angiography (DSA) were enrol ed. Each lower extremity artery was divided into 11 segments. The arteries were defined as normal, mild, moderate or severe stenosis or occlusion based on vessel lesions. The sensitivity, specificity and diagnostic accuracy of CTA in evaluating vessel lesions were determined according to the results of DSA. Results A total of 1121 segments were evaluated by both CTA and DSA. Arterial stenosis or occlusion was diagnosed by DSA in 502 segments. The sensitivity and specificity of CTA for diagnosis of arterial occlusion were 96.9% and 97.7%, respectively (Kappa was 0.786, P<0.05). There was no significant difference between DSA and CTA in grading stenosis of lower extremity arteries (Z value = 0.933, P<0.05). Conclusion CTA is a reliable, effective and noninvasive method for the preoperative evaluation of lower extremity ASO.
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