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Abstract Objective To explore clinical efficacy of radiofrequency catheter ablation of non- pulmonary vein (PV) focus in paroxysmal atrial fibril ation (PAF). Methods 298 consecutive PAF patients (203 males, age 63.0±10.4 years) underwent ablation were divided into group A (243 patients) without non- PV ectopy, group B (32 patients) with non- PV ectopy as the trigger of PAF and ablated successfully, and group C (23 patients) with non- PV ectopy as the trigger of PAF but not ablated completely. Clinical features, distribution of foci and ablation results were compared between groups. Results Clinical features and the incidence of PV focus were similar in the three groups. The rate of superior vena cava isolation, linear ablation of left atrial roof and floor were significantly higher in group B and C than in group A. The recurrence rate of atrial fibril ation was significantly higher in group C(68%) than in group A(9.8%) and group B(8.8%) during fol ow up of (25.3 ±10.6)months (P<0.01). Conclusion Inducing and successful y ablating non- pulmonary vein ectopy may improve the success rate of procedure in patients with PAF.
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