|
Abstract Objective To investigate the correlation of serum uric acid level with NT- proBNP and GRACE risk score in elderly patients with acute coronary syndrome (ACS). Methods 143 elderly patients with ACS were classified by quartile of serum uric acid on admission:group I (uric acid<278.32μmol/L), groupⅡ (287.33~334.46μmol/L), groupⅢ(334.47~386.26μmol/L), groupⅣ(uric acid>386.27μmol/L). NT- proBNP, creatine kinase isoenzyme(CK- MB), troponin I (cTnI) were measured and GRACE risk score was calculated. The association of serum uric acid with NT- proBNP and GRACE risk score was analyzed. Results NT- proBNP, GRACE risk score, cTnI and CK- MB were significantly higher in group IV [(803.38±235.47)pg/ml,(138.3±42.5),(5.49±1.54)μg/L,(68.37±18.45)μg/L] than in group I [(326.56±71.30), (103.4±20.4), (1.81±0.53), (42.29±12.30)], grouo II[(295.5±55.82), (96.3±18.8), (1.62±0.45), (38.29±10.89)]and group III[(567.39±125.73), (126.4±35.4), (3.67±1.22), (56.49±13.44)](al P<0.05). These were significantly higher in group III than in groupⅠand Ⅱ (al P<0.05);Pearson correlation analysis showed that serum uric acid was positively related to NT-proBNP and GRACE risk score(r=0.432、0.365, P<0.05). Conclusion Serum uric acid level is related to NT- proBNP and GRACE risk score in elderly patients with ACS.
|
|
|
|
|
|
