|
Abstract Objective To investigate the value of heart rate turbulence (HRT) in predicting potential y malignant ventricular arrhythmia (VA) in dilated cardiomyopathy patients. Methods 45 patients with dilated cardiomyopathy were divided into benign VA group (n=16) and potential y malignant VA group (n=29) . 30 healthy individuals were included as control group. They underwent 24 h dynamic ECG examination. HRT onset(TO) and turbulence slope(TS) were calculated and compared between groups. The sensitivity, specificity, positive and negative predictive value of TO≥0, TS≤2.5ms / R- R, TO≥0+TS≤2.5ms / R- R were analyzed. Results TS was significantly lower and TO was higher in benign VA group [(4.68±3.87)%], (- 0.11±3.16)%] and potential y malignant VA group [(2.48±2.76)%, (1.17±2.08)%] than that in control group [(9.08±5.57)%,(- 2.96±3.42)%](al P<0.01). TS was significantly lower and TO was higher in potential y malignant VA group than in benign VA group (P<0.05). The sensitivity, specificity, positive and negative predictive value of TS <2.5ms / R- R (79.37%, 93.48%, 88.46%, 87.76%) were higher than those of TO≥0 (75.86%, 82.61%, 73.33%, 84.44%), respectively. The combination of TO≥0 and TS≤2.5ms/R- R yielded the highest specificity and positive predictive value, but the lowest sensitivity and negative predictive value. Conclusion HRT is impaired in dilated cardiomyopathy patients. TS may be a predictor of potential y malignant VA in patients with dilated cardiomyopathy.
|
|
|
|
|
|
