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Abstract Objective To explore ECG characteristics of idiopathic premature ventricular contractions (PVCs)and the efficacy and safety of radiofrequency catheter ablation (RFCA). Methods 351 patients with symptomatic PVCs under-went RFCA. Ablation was performed by a catheter with temperature control guided by pace mapping and activation se-quence mapping. The end point of the procedure was that PVCs disappeared and could not been induced by intravenous isoproterenol. 24- hour Holter monitor was performed at 1 month, 6 month, 1 year and 2 year, respectively, after operation. Results 291 cases(67.8%female)had PVCs from right ventricle and 60 cases from left ventricle(60.0%male). The ma-jority of PVCs originated from right ventricular outflow tract, the rest from tricuspid annulus, aortic sinus and left ventricular septum. The success rate of ablation of PVCs from left and right ventricle were 80.0% and 93.5%,respectively. 13 cases had PVCs recurred in 2 years and 31 cases were lost to fol ow- up. Conclusion RFCA of PVCs is safe and effective. The ECG features and ablation success rate vary with origins of PVCs.
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