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Abstract Objective To evaluate the value of ventricular activation time (VAT) in limb leads on ECG in the diagnosis of left ventricular hypertrophy. Methods VAT in lead I and III was measured and compared to left ventricular mass deter-mined by echocardiography in 116 patients with hypertension. Results The VAT was highly correlated with left ventricu-lar mass (r=0.88 in male, r=0.70 in female, P<0.01). The sensitivity of VAT 0.04s in the diagnosis of hypertensive left ven-tricular hypertrophy was significantly higher than that of routine electrocardiographic criteria (80.1% vs. 22.2%~51.7%, P<0.01). Conclusion The VAT in limb leads is of significance for diagnosing hypertensive left ventricular hypertrophy.
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