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Abstract Objective To determine whether the efficacy and restenosis rate of domestic biodegradable polymer drug- eluting stents(EXCEL) is superior to that of domestic non- biodegradable polymer drug- eluting stents (PARTNER) in the treatment of coronary artery disease (CAD). Methods 111 cases with CAD underwent percutaneous coronary intervention (PCI). Of them, 54 patients were implanted with EXCEL stents and 57 patients with PARTNER stents. Main adverse cardiac events(MACE), recurrent angina, late stent thrombosis, restenosis rate, in- stent lumen loss and heart failure were observed during follow- up. Results There was no significant difference of the incidence of MACE, recurrent angina, late stent thrombosis, restenosis rate and heart failure between the two groups during fol ow- up of 6 to 30 months (al P>0.05). The percent of in- stent lumen loss≥30% was significant lower in EXCEL group (1.9%) than in PARTNER group (14.0%) (P=0.019). Conclusion The efficacy and safety of EXCEL stent in the treatment of CAD are similar to that of PARTNER stent, while the percent in- stent lumen loss is lower.
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