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Abstract Objective To assess the association between the efficacy of percutaneous coronary intervention (PCI) and QRS pattern in patients with severe heart failure. Methods 122 patients with severe heart failure from January 2011 to May 2014 were enrol ed. They were divided into fragmented QRS (fQRS) group (62 cases) and non- fragmented QRS (nfQRS) group (60 cases) based on ECG recorded at admission. Left ventricular ejection fraction (LVEF), left ventricular end- diastolic volume index (LVEDVI), 6- minute walking test (6 MWT) and prognosis were compared between the two groups. Results LVEF, LVEDVI and 6MWT were similar between the two groups before PCI. Al these parameters were improved significantly after PCI in both groups (t=2.172、2.144、2.158,2.043、2.077、2.018, P<0.05) and more significantly in nfQRS group than in fQRS group (t=2.133、2.058、2.107, P<0.05). The incidences of cardiac shock, arrhythmia, severe atrioventricular block and death were significantly higher in fQRS group than in nfQRS group (χ2= 4.307, 5.302, 4.441, 5.302, P<0.05). Conclusion PCI may improve severe heart failure, especial y in patients with nfQRS.
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