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Abstract Objective To analyze clinical characteristics and associated factors of left ventricular free wall rupture (FWR) after acute myocardial infarction (AMI) in elderly patients. Methods Clinical data of 19 AMI elderly patients complicated with FWR (FWR group) were retrospectively analyzed and compared with that of 35 AMI patients without mechanical complication (control group). Multivariate logistic regression analysis was performed to identify associated factors of FWR. Results 17 cases were diagnosed as ST elevated AMI(FWR group), of them, 10 had anterior infarction. FWR occurred within a week after AMI in 16 cases, with average of 3.50±3.07day. 12 cases developed FWR at the period of 14:00- 19:00. Undue physical exertion or other causes were documented in 8 patients with FWR. The incidence of anterior myocardial infarction, the level of plasma serum creatinine (P<0.05), brain natriuretic peptide,high sensitive C- creative protein (P<0.01) were significantly higher, while the levels of hematocrit and LDL- C were significantly lower in FWR group than in control group (P<0.01 or 0.05). Multivariate logistic regression analysis revealed that hematocrit and serum creatinine to be associated with FWR. Conclusion The risk of FWR may increase in elderly AMI patients with lower serum hematocrit and higher serum creatinine.
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