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Abstract Objective To assess the clinical efficacy and safety of catheter ablation of paroxysmal supraventricular tachycardia(PSVT)guided by Ensite- NavX system. Methods 80 patients with PSVT were enrol ed. Ablation was guid-ed by Ensite- NavX system in 40 cases (Ensite group)and by conventional mapping in another 40 cases(conventional group). The procedure time, fluoroscopic time, the number of energy application, the effectiveness of energy application, the success rate and 1- year recurrence rate were compared between the two groups. Results 23 cases had AVNRT and 17 cases had AVRT[6 right- sided accessory pathways(AP), 11 left- sided APs]in Ensite group. 21 cases had AVNRT and 19 cases had AVRT(6 right- sided APs, 13 left- sided APs)in conventional group. Al cases were ablated successful y without serious complication. Fluoroscopic time was significantly shorter in Ensite group [(5.1±1.3)min,(1.3±0.2)min, (1.2±0.2)min] than in conventional group [(10.3±2.3)min,(25.3±7.8)min,(17.7±4.8)min](al P<0.05). Ensite group was superior to conventional group in the procedure time [(48.1±12.5)min vs (59.7±13.3)min, P<0.05;(41.6±10.3)min vs (54.3±12.2)min, P<0.05], the number of energy application (3.7±0.5vs 5.8±1.1, P<0.05;2.8±0.6 vs 4.1±0.8, P<0.05), and effectiveness of energy application [(48.3±13.1)%vs(31.3±11.1)%, P<0.05;(52.4±13.7)%vs(41.3±11.8)%, P<0.05)] of right- sided APs/AVNRT ablation, but inferior to conventional group in the procedure time[(51.7±11.3)min vs (32.3±8.5)min, P<0.05], the number of energy application ( 5.7±0.6 vs 3.1±0.7, P<0.05)and effectiveness of energy application [(32.3±10.3)%vs(54.7±13.3)%, P<0.05]of left- sided APs. There was no significant difference of 1- year re-currence rate between the two groups. Conclusion Ablation guided by Ensite- NavX system is efficient and feasible for PSVT, especial y right- sided APs and AVNRT.
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