|
Abstract Objective To observe clinical effects of cardiac resynchronization therapy for chronic heart failure patients with narrow QRS wave. Methods Five chronic heart failure patients with narrow QRS wave were treated with synchronous biventricular pacing. Physical activity, heart function, night heart rate, standard deviation of heart period (SDNN) and left ventricular (LV) ejection fraction were evaluated during follow-up of 15.6 ～ 12.1months. The standard deviation of time to peak systolic velocity (Ts-SD) of 12 LV myocardial segment was calculated on tissue Doppler imaging. The dispersion (Tmsv-Dis) and maximum difference (Tmsv-Dif) of time to minimum regional volume of LV segment 16, 12 and 6 were calculated on 3D echocardiography, respectively. Results After treatment, NYHA class decreased from Ⅲ～Ⅳ IV to Ⅱ～Ⅲ and night heart rate from (85.0±3.6) bpm to (62.3±2.5) bpm, while daily physical activity increased from (0.03±0.05) h to (2.93 ± 1.10) h, SDNN from(48.3 ± 7.6)ms to(116.7±5.8)ms and LV ejection fraction from (21.2± 4.5)% to (34.7 ± 5.1)%(all P < 0.05). Ts-SD, Tmrv-Dis and Tmrv-Dif decreased significantly (all P < 0.05). Conclusion Chronic heart failure patients with narrow QRS wave may receive cardiac resynchronization therapy when LV dyssynchrony is ascertained by echocardiography and tissue Doppler imaging.
|
|
|
|
|
|
